Synthesis, structural characterization, and biological evaluation of copper(II)–quinazolin-4-one coordination complexes

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Baymuratova Gulbaxar Orinbayevna
Foziljon Ergashevich Saitkulov
Zoid Zohidovich Mirvaliyev
Rajab Akbarovich Samiyev
Muratbay Shamshetovich Turimbetov

Abstract

In this work, quinazolin-4-one and copper (II) nitrate are used as ligands to investigate the synthesis of coordination compounds. The complexes were created by a controlled reaction and examined using a range of spectroscopic methods, such as XRD, UV-Vis, and infrared. The effective coordination of copper(II) ions with quinazolin-4-one was validated by the structural analysis. The produced compounds' antibacterial and antioxidant properties were assessed using biological tests. Significant biological activity was shown in the results, indicating possible uses in the agricultural and medicinal sectors. This study advances our knowledge of metal-ligand interactions and how they can improve biological efficacy.

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Baymuratova Gulbaxar Orinbayevna, Foziljon Ergashevich Saitkulov, Zoid Zohidovich Mirvaliyev, Rajab Akbarovich Samiyev, & Muratbay Shamshetovich Turimbetov. (2026). Synthesis, structural characterization, and biological evaluation of copper(II)–quinazolin-4-one coordination complexes. Partner Conferences of the International Scientific Journal Research Focus, 438-442. https://doi.org/10.66073/ReFocus-Conf/0910082

References

Sapaev, B., Saitkulov, F. E., Tashniyazov, A. A., & Normurodov, O. U. (2021). Study of methylation reactions of 2-phenylquinazoline-4-tion with “soft” and “hard” methylation agents and determination of its biological activity. In E3S Web of Conferences (Vol. 258, p. 04023). EDP Sciences. DOI: https://doi.org/10.1051/e3sconf/202125804023

Sapaev, B., Sapaev, I. B., Saitkulov, F. E., Tashniyazov, A. A., & Nazaraliev, D. (2022, June). Synthesis of 2-methylquinazoline-4-thione with the purpose of alkylation of 3-propyl 2-methylquinazoline-4-thione with alkylating agents. In AIP Conference Proceedings (Vol. 2432, No. 1). AIP Publishing. DOI: https://doi.org/10.1063/5.0089924

Saitkulov, F., Ahmatov, I., Meliboyeva, F., Saydaxmatova, D., & Turopova, S. (2022). Titrimetric analysis of calcium cation in" obi navvot" variety of melon. Академические исследования в современной науке, 1(19), 302-304.

Boymuratova, G. O., Saitkulov, F. E., Nasimov, K. M., & Tugalov, M. (2022). To Examine the Processes of Biochemical Action Of 6-Benzylaminopurine with Cobalt-II Nitrate Dihydrate on the “Morus Alba” Variety of Moraceae Plant. Eurasian Journal of Physics, Chemistry and Mathematics, 3, 39-42.

Saitkulov, F., Abdusattorova, D., Ismoilova, U., Xasanova, D., & Xusanova, M. (2022). Study of the effect of fertilizing on grain productivity. Development and innovations in science, 1(17), 32-35.

Саиткулов, Ф. Э., Гиясов, К., & Элмурадов, Б. Ж. (2022). Метилирование 2-метилхиназолин-4-она «мягкими» и «жесткими» метилирующими агентами. Universum: химия и биология, (11-2 (101)),49

Sapayev, B., Saitkulov, F. E., Normurodov, O. U., Haydarov, G., & Ergashyev, B. (2023). Studying Complex Compounds of Cobalt (II)-Chlooride Gecsacrystolohydrate with Acetamide and Making Refractory Fabrics from Them.

Saitkulov, F., Abdukadirov, S., Ashurova, N., Turapov, J., & Zoxidjonova, A. (2022). Recommendations for the use of fats. Theoretical aspects in the formation of pedagogical sciences, 1(7), 175-177.

Saitkulov, F., Begimqulov, I., Oʻralova, N., Gulimmatova, R., & Rahmonqulova, D. (2022). Biochemical effects of the coordination compound of cobalt-ii nitrate quinazolin-4-one with 3-indolyl acetic acid in the “amber” plants grades phaseolus aureus. Академические исследования в современной науке, 1(17), 263-267.

Saitkulov, F., Uralova, B., Ermonova, O., Mamurova, M., & Karimova, K. (2022). Biochemical nutrition family plant rute-lemon leaved. Академические исследования в современной науке, 1(17), 268-273.

Саиткулов, Ф. Э., & Элмурадов, Б. Ж. (2022). УФ-спектральные характеристики хиназолин-4-он и–тионов. In Innovative developments and research in education international scientific-online conference. pp-10-12.

Saitkulov, F., Eshqobilov, J., Turgunova, N., & Xamidov, A. (2022). Plant nutrition, the process of absorption. Current approaches and new research in modern sciences, 1(7), 25-29.