Antimicrobial screening and molecular identification of active endophytic bacterial isolates from Ferula varia

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Published: 2026-10-30
DOI: https://doi.org/10.66073/ReFocus-Conf/3010016
Keywords:
Ferula varia, endophytic bacteria, antimicrobial activity, inhibition zone, 16S rRNA gene sequencing, molecular identification, antimicrobial metabolites

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Murodullayev Dilmurod Dilshodovich
Institute of Microbiology of the Academy of Sciences of the Republic of Uzbekistan
Alimova Dildora Farkhod kizi
Institute of Microbiology of the Academy of Sciences of the Republic of Uzbekistan
Temirova Marguba
Karshi State University
Rayimberdiyeva Sanobar
Karshi State University
Absattorova Khursanoy
Karshi State University
Rustamova Nigora
Institute of Microbiology of the Academy of Sciences of the Republic of Uzbekistan

Abstract

Endophytic bacteria from medicinal plants are a promising source of antimicrobial metabolites, and this study evaluated the endophytic isolates of Ferula varia (more than 40 isolates from roots, stems, leaves, and flowers) against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Bacillus subtilis, and Candida albicans. Six isolates showed antimicrobial activity and were identified by 16S rRNA gene sequencing as Bacillus pumilus, B. atrophaeus, B. rugosus, and Serratia odorifera, with the sequences deposited in NCBI GenBank. Four of these isolates (FV1i, FV3i, FVP1.1, and FVB1) were active against all five test organisms, making them promising candidates for further study of their bioactive metabolites.

Article Details

Issue

Vol. 1 No. 8 (2026): Status and Development Prospects of Fundamental and Applied Microbiology: The Viewpoint of Young Scientists

Section

Fundamental and Applied Microbiology
Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

Murodullayev Dilmurod Dilshodovich, Alimova Dildora Farkhod kizi, Temirova Marguba, Rayimberdiyeva Sanobar, Absattorova Khursanoy, & Rustamova Nigora. (2026). Antimicrobial screening and molecular identification of active endophytic bacterial isolates from Ferula varia. Partner Conferences of the International Scientific Journal Research Focus, 1(8), 74-76. https://doi.org/10.66073/ReFocus-Conf/3010016

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