Za’faron (Crocus sativus L.) o‘simligidan ajratilgan endofit zamburug‘larning antikoagulyant faolligi

Anticoagulant activity of endophytic fungi isolated from saffron (Crocus sativus L.)

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Published: 2026-10-30
DOI: https://doi.org/10.66073/ReFocus-Conf/3010064
Keywords:
Crocus sativus L, anticoagulant activity, plasma recalcification time (PRT), Penicillium sp

Main Article Content

Kuziyeva Nilufar Khusanboy kizi
Institute of Microbiology of the Academy of Sciences of the Republic of Uzbekistan
Abdulmyanova Liliya Ilyasovna
Institute of Microbiology of the Academy of Sciences of the Republic of Uzbekistan
Shodiyeva Dildora Giyosovna
Institute of Microbiology of the Academy of Sciences of the Republic of Uzbekistan

Abstract

This study evaluated the anticoagulant activity of secondary metabolites produced by endophytic fungi isolated from Crocus sativus L. (saffron). Extracts of 17 fungal strains were tested using the plasma recalcification time (PRT) assay. The results revealed differences in the activity of the tested samples. The most pronounced effect was observed in the Penicillium sp. CS50R isolate, for which the PRT exceeded 120 minutes. This isolate represents a promising source of biologically active compounds with potential anticoagulant properties. The findings provide a basis for further investigation of the anticoagulant activity of saffron-associated endophytic fungi and the identification of active metabolites.

Article Details

Issue

Vol. 1 No. 8 (2026): Status and Development Prospects of Fundamental and Applied Microbiology: The Viewpoint of Young Scientists

Section

Probiotics, Food and Pharmaceutical Microbiology
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This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

Kuziyeva Nilufar Khusanboy kizi, Abdulmyanova Liliya Ilyasovna, & Shodiyeva Dildora Giyosovna. (2026). Anticoagulant activity of endophytic fungi isolated from saffron (Crocus sativus L.). Partner Conferences of the International Scientific Journal Research Focus, 1(8), 234-237. https://doi.org/10.66073/ReFocus-Conf/3010064

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