Streptomyces spectabilis IMB Uz-1 quruq biomassasi va prodigiozinning in vivo sharoitda o‘tkir toksikligini baholash

In vivo assessment of the acute toxicity of Streptomyces spectabilis IMB Uz-1 dry biomass and prodigiosin

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Published: 2026-10-30
DOI: https://doi.org/10.66073/ReFocus-Conf/3010066

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Abdunazarov Nomonjon
Institute of Microbiology of the Academy of Sciences of the Republic of Uzbekistan
Mamarasulov Bahodir Dalikhonovich
Institute of Microbiology of the Academy of Sciences of the Republic of Uzbekistan
Boymatova Muslima
Namangan Branch of the Republican Center for Advanced Training and Specialization of Medical and Pharmaceutical Workers

Article Details

Issue

Vol. 1 No. 8 (2026): Status and Development Prospects of Fundamental and Applied Microbiology: The Viewpoint of Young Scientists

Section

Probiotics, Food and Pharmaceutical Microbiology
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This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

Abdunazarov Nomonjon, Mamarasulov Bahodir Dalikhonovich, & Boymatova Muslima. (2026). In vivo assessment of the acute toxicity of Streptomyces spectabilis IMB Uz-1 dry biomass and prodigiosin. Partner Conferences of the International Scientific Journal Research Focus, 1(8), 241-244. https://doi.org/10.66073/ReFocus-Conf/3010066

References

No’monjon, A. Bahodir, M. (2025). Streptomyces spectabilis fermentatsiyasida muhit sharoitlarini ahamiyati. Scientific journal of the Fergana State University, (5), 136-136.

Chen, Y., Luo, G., Chen, S., Zhang, D., Xie, W., Wang, Z., & Xu, H. (2021). The potential of prodigiosin for control of Prorocentrum donghaiense blooms: Algicidal properties and acute toxicity to other marine organisms at various trophic levels. Ecotoxicology and Environmental Safety, 228, 112913. DOI: https://doi.org/10.1016/j.ecoenv.2021.112913

Islan, G. A., Rodenak-Kladniew, B., Noacco, N., Duran, N., & Castro, G. R. (2022). Prodigiosin: A promising biomolecule with many potential biomedical applications. Bioengineered, 13(6), 14227-14258. DOI: https://doi.org/10.1080/21655979.2022.2084498

Srilekha, V., Krishna, G., Sreelatha, B., Jagadeesh Kumar, E., & Rajeshwari, K. V. N. (2024). Prodigiosin: A fascinating and the most versatile bioactive pigment with diverse applications. Systems Microbiology and Biomanufacturing, 4(1), 66-76. DOI: https://doi.org/10.1007/s43393-023-00192-1

Lu, Y., Liu, D., Jiang, R., Li, Z., & Gao, X. (2024). Prodigiosin: unveiling the crimson wonder–a comprehensive journey from diverse bioactivity to synthesis and yield enhancement. Frontiers in Microbiology, 15, 1412776. DOI: https://doi.org/10.3389/fmicb.2024.1412776

No’monjon, A. Bahodir, M. Kakhramon D. Muslima B. Dilfuza J. (2026) Isolation, identification, and characterization of Streptomyces spectabilis strain with antimicrobial activity against selected human pathogens. Science and innovation International Scientific Journal 2026;5(3):111–127.

Organisation for Economic Co-operation and Development. (2002). Test No. 423: acute oral toxicity-acute toxic class method. OECD Publishing.

Raval, K., & Tirgar, P. (2024). Acute oral toxicity evaluation of p-propoxybenzoic acid in Sprague-Dawley rats according to OECD guideline 425–Up and down method. Indian Journal of Physiology and Pharmacology, 68(4), 281-287. DOI: https://doi.org/10.25259/IJPP_21_2024