Cervicovaginal dysbiosis as a cofactor of persistent human papillomavirus infection and progression of cervical neoplasia

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Published: 2026-10-30
DOI: https://doi.org/10.66073/ReFocus-Conf/3010122
Keywords:
human papillomavirus, cervicovaginal microbiota, dysbiosis, Lactobacillus, bacterial vaginosis, CIN

Main Article Content

Abdullayeva Madinakhon Isokjon kizi
Namangan Branch of Kimyo International University in Tashkent

Abstract

Studies published in 2011–2025 on the role of cervicovaginal dysbiosis in the persistence of high-risk human papillomavirus (HPV) and the progression of cervical intraepithelial neoplasia (CIN) were analysed. The Lactobacillus-depleted community state CST IV, dominated by anaerobic bacteria, increases the odds of HPV detection, and its share rises from 10% in normal cytology to 40% in invasive cancer. Assessment of the microbiocenosis in HPV-positive women may improve risk stratification.

Article Details

Issue

Vol. 1 No. 8 (2026): Status and Development Prospects of Fundamental and Applied Microbiology: The Viewpoint of Young Scientists

Section

Infectious Diseases, Immunology and Laboratory Diagnostics
Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

Abdullayeva Madinakhon Isokjon kizi. (2026). Cervicovaginal dysbiosis as a cofactor of persistent human papillomavirus infection and progression of cervical neoplasia. Partner Conferences of the International Scientific Journal Research Focus, 1(8), 434-436. https://doi.org/10.66073/ReFocus-Conf/3010122

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