Oqsil kasalligiga qarşi emlaş samaradorligini baholaşda postvaksinal serologik monitoringning ahamiyati

Abstract

This article highlights the scientific and practical significance of using serological monitoring to assess post-vaccination immunity in vaccinated farm animals. The study included 250 animals: 120 cattle, 80 sheep, and 50 goats. Blood serum samples were analyzed prior to vaccination and at 7, 14, 21, 30, 60, and 90 days post-vaccination. Antibodies against structural proteins of the foot-and-mouth disease virus were detected using the SP-ELISA method. To assess potential contact with the wild-type virus, selected samples were also tested using NSP-ELISA. The study found that the proportion of animals possessing protective antibodies rose from 40.0% at the time of vaccination to 87.6% by day 30; this figure stood at 84.0% on day 60 and 78.0% on day 90. The highest rates of post-vaccination seropositivity were observed in cattle. The results demonstrate that post-vaccination serological monitoring provides a basis for evaluating actual population immunity, identifying unprotected animals, and determining appropriate revaccination schedules, rather than merely measuring vaccination coverage.