Naslli sigirlarda subklinik endometrit kasalligining etiologiyasi va patogenezi

Etiology and pathogenesis of subclinical endometritis in pedigree cows

Main Article Content

Gayratdin Sharibay ulı Omirzakov
Maryam Maksetbay qizi Yesboganova

Abstract

Based on an analysis of international and local scientific literature, this article describes the etiology and pathogenesis of subclinical endometritis, the pathology that is most frequently encountered in high-yielding pedigree cows in the postpartum period and causes great economic losses because of its latent course. The study fully reveals the interplay of infectious factors (Escherichia coli, Trueperella pyogenes, etc.), metabolic imbalance and energy balance, hypocalcemia and obstetric pathologies as causes of the disease. In addition, the persistence of high numbers of polymorphonuclear neutrophils in the uterine mucosa, the synthesis of inflammatory cytokines and the mechanisms of their negative effect on the hypothalamic–pituitary–ovarian axis and on embryo implantation are analyzed scientifically.

Article Details

Section

Veterinary medicine and animal health

How to Cite

Omirzakov, G. S. ulı, & Yesboganova, M. M. qizi. (2026). Etiology and pathogenesis of subclinical endometritis in pedigree cows. Partner Conferences of the International Scientific Journal Research Focus, 1(10), 202-206. https://doi.org/10.66073/ReFocus-Conf/1311038

References

Kasimanickam, R., Duffield, T. F., Foster, R. A., Gartley, C. J., Leslie, K. E., Walton, J. S., & Johnson, W. H. (2004). Endometrial cytology and ultrasonography for the detection of subclinical endometritis in postpartum dairy cows. Theriogenology, 62(1-2), 9–23. DOI: 10.1016/j.theriogenology.2003.03.004 | PMID: 15159097 DOI: https://doi.org/10.1016/j.theriogenology.2003.03.001

Sheldon, I. M., Cronin, J., Goetze, L., Donofrio, G., & Schuberth, H. J. (2009). Defining postpartum uterine disease and the mechanisms of infection and immunity in the female reproductive tract in cattle. Biology of Reproduction, 81(6), 1025–1032. DOI: 10.1095/biolreprod.109.077370 | PMID: 19439727 DOI: https://doi.org/10.1095/biolreprod.109.077370

LeBlanc, S. J. (2012). Interactions of metabolism, inflammation, and reproductive tract health in dairy cows. Veterinary Clinics of North America: Food Animal Practice, 28(3), 479–496. DOI: 10.1016/j.cvfa.2012.07.002 | PMID: 22981198 DOI: https://doi.org/10.1016/j.cvfa.2012.07.002

Gilbert, R. O., Shin, S. T., Guard, C. L., Erb, H. N., & Frajblat, M. (2005). Prevalence of endometritis and its effects on reproductive performance of dairy cows. Theriogenology, 64(9), 1879–1888. DOI: 10.1016/j.theriogenology.2005.04.024 | PMID: 15961149 DOI: https://doi.org/10.1016/j.theriogenology.2005.04.022

Esposito, G., Irons, P. C., Webb, E. C., & Chapwanya, A. (2014). Interactions between negative energy balance, metabolic diseases, uterine health and immune response in transition dairy cows. Animal Reproduction Science, 144(3-4), 60–71. DOI: 10.1016/j.anireprosci.2013.11.007 | PMID: 24368171 DOI: https://doi.org/10.1016/j.anireprosci.2013.11.007

Pascottini, O. B., LeBlanc, S. J., Gnemi, G., Leroy, J. L. M. R., & Opsomer, G. (2023). Genesis of clinical and subclinical endometritis in dairy cows. Reproduction, 166(2), R15–R24. DOI: 10.1530/REP-22-0452 | PMID: 37294111 DOI: https://doi.org/10.1530/REP-22-0452