VARIANTS OF CLINICAL COURSE AND METHODS OF TREATMENT OF VIRAL HEPATITIS DELTA
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Abstract
Hepatitis D is an inflammation of the liver caused by the hepatitis D virus (HDV), which
requires hepatitis B virus (HBV) for its replication. Hepatitis D infection cannot occur in the absence of
HBV. HDV–HBV co-infection is considered the most severe form of chronic viral hepatitis due to more
rapid progression towards hepatocellular carcinoma and liver-related death. Vaccination against hepatitis
B can prevent HDV infection. HDV has recently been classified as carcinogenic to humans (class I) by the
IARC mongraph programme, just like hepatitis B and C.
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